DNMBP

Across TCGA patient cohorts, DNMBP RNA expression is significantly associated with the protein abundance of many other proteins, with 15,894 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DNMBP-associated proteins across cancer lineages are TYROBP, THEMIS2, and SLK. Each is linked with DNMBP in more than 5 cancer types. Because this analysis shows association rather than direction, both DNMBP-to-partner and partner-to-DNMBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNMBP versus TYROBP in PDAC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNMBP→partner) and Y-score (partner→DNMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TYROBP →	-0.768	-0.493	<.001	<.001	3	6
UCEC	THEMIS2 →	-0.462	-0.491	<.001	<.001	3	6
BRCA	SLK →	+0.310	+0.880	<.001	<.001	3	6
PDAC	PIK3CG_S974 →	-0.702	-0.408	<.001	.001	3	5
PDAC	PLEKHA1 →	+0.458	+0.578	<.001	<.001	3	5
UCEC	THEMIS2_T593 →	-0.826	-0.787	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,894 associations by consensus.

DNMBP vs TYROBP — PDAC

Explore this scatter interactively →