DNMBP

Across TCGA cell cohorts, DNMBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,851 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DNMBP-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Hepatocyte growth factor receptor signaling pathway, and Positive regulation of protein binding. Each is linked with DNMBP in more than 12 cancer types. Because this analysis shows association rather than direction, both DNMBP-to-partner and partner-to-DNMBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by DNMBP-low versus DNMBP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNMBP→partner) and Y-score (partner→DNMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cell-substrate junction organization →	+0.182	+0.859	<.001	.001	3	13
LIVER	Hepatocyte growth factor receptor signaling pathway →	+0.220	+1.406	.001	.002	2	12
LUNG_NSCLC_LUSC	Positive regulation of protein binding →	+0.119	+1.734	<.001	<.001	3	10
KIDNEY	Regulation of epidermal growth factor receptor signaling pathway →	+0.057	+1.003	.007	.002	2	11
BLOOD_Lymphoma	Response to ionizing radiation →	+0.048	+1.413	<.001	.001	3	9
BONE	Regulation of cell-matrix adhesion →	+0.122	+0.728	.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,851 associations by consensus.

Positive regulation of cell-substrate junction organization by DNMBP expression — BONE

Explore this box plot interactively →