DNMBP-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DNMBP-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated DNMBP-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher DNMBP-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DNMBP-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and MESO show a favorable association.

HNSC, MESO, and KIRC are the cancer types where DNMBP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileIII,IV0.7840.572<.00165view →
MESODFSQuartileII,III,IV0.4790.218<.00161view →
KIRCOSTertileAll0.7680.559<.00158view →
UCECDFSMedianIII,IV0.8740.711.00154view →
LGGOSMedianAll0.8990.720<.00153view →
BRCAOSTertileIII,IV0.9140.740<.00147view →
SKCMOSMedianII,III,IV0.5390.198.00123view →
ACCOSMedianIII,IV0.1740.714.00218view →
LIHCDFSTertileAll0.5560.378.00218view →
SARCDFSTertileAll0.7550.475.00116view →
STADOSMedianAll0.6290.503.01612view →
UCSOSTertileIV0.6650.296.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

Exploration