Across TCGA patient cohorts, DNM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,068 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNM3-associated proteins across cancer lineages are RPL6, ISLR, and CNN3. Each is linked with DNM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNM3-to-partner and partner-to-DNM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3→partner) and Y-score (partner→DNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL6 →	-0.439	-0.690	<.001	<.001	3	6
OV	ISLR →	+0.723	+0.537	.003	.003	3	6
OV	CNN3 →	+0.612	+0.598	.001	.001	3	6
OV	FHL3 →	+0.667	+0.603	.001	.003	3	6
COAD	HDGFL3 →	+0.724	+0.430	<.001	.003	3	6
BRCA	PHLDB1 →	+0.594	+0.778	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,068 associations by consensus.

Exploration

DNM3 survival (RNA) · tumor vs normal (RNA) · all DNM3 data types