Across TCGA patient cohorts, DNM3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,832 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNM3-associated genes across cancer lineages are SHROOM4, PDE2A, and FHL5. Each is linked with DNM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNM3-to-partner and partner-to-DNM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3→partner) and Y-score (partner→DNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SHROOM4 →	+0.771	+0.712	.006	.005	3	6
GBM	PDE2A →	+1.311	+0.710	<.001	<.001	3	6
BRCA	FHL5 →	+1.154	+0.630	.005	.009	3	5
UCEC	CNRIP1 →	+0.818	+0.472	.002	.001	3	5
GBM	FXYD6 →	+1.025	+0.417	<.001	.003	3	5
CCRCC	PIEZO2 →	+0.804	+0.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,832 associations by consensus.

Exploration

DNM3 survival (RNA) · tumor vs normal (RNA) · all DNM3 data types