Across TCGA patient cohorts, DNM3 protein abundance is significantly associated with the protein abundance of many other proteins, with 27,235 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNM3-associated proteins across cancer lineages are CAVIN2, TMOD2, and LDB3. Each is linked with DNM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNM3-to-partner and partner-to-DNM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3→partner) and Y-score (partner→DNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CAVIN2 →	+0.799	+0.396	<.001	<.001	3	6
GBM	TMOD2 →	+0.679	+0.843	<.001	<.001	3	6
GBM	LDB3 →	+0.705	+0.617	<.001	<.001	3	6
UCEC	ARHGAP31 →	+0.360	+0.411	<.001	<.001	3	5
GBM	APBB1 →	+0.338	+0.749	<.001	<.001	3	5
GBM	CCDC85A_S255 →	+0.952	+0.713	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,235 associations by consensus.

Exploration

DNM3 survival (RNA) · tumor vs normal (RNA) · all DNM3 data types