Across TCGA cell cohorts, DNM3 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DNM3-associated genes across cancer lineages are FABP12, LCT, and FAM205A. Each is linked with DNM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNM3-to-partner and partner-to-DNM3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3→partner) and Y-score (partner→DNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FABP12 →	+0.116	+4.981	.002	.008	3	2
LUNG_NSCLC_LUAD	LCT →	+0.122	+3.612	<.001	.004	3	2
LARGE_INTESTINE	FAM205A →	+0.017	+3.029	<.001	.003	3	2
BONE	GZMH →	+0.038	+4.129	<.001	.001	3	1
BONE	CDX4 →	+0.010	+4.129	<.001	.001	3	1
BONE	HTR3D →	+0.012	+4.129	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

DNM3 survival (RNA) · tumor vs normal (RNA) · all DNM3 data types