DNM2

Across TCGA cell cohorts, DNM2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNM2-associated genes across cancer lineages are SIN3B, TIMM29, and YIPF2. Each is linked with DNM2 in more than 14 cancer types. Because this analysis shows association rather than direction, both DNM2-to-partner and partner-to-DNM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNM2 versus SIN3B in BONE, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM2→partner) and Y-score (partner→DNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	SIN3B →	+1.347	+0.820	<.001	<.001	3	14
BLOOD_Myeloma	TIMM29 →	+1.066	+0.717	<.001	<.001	3	14
OVARY	YIPF2 →	+1.214	+0.731	<.001	<.001	2	15
UPPER_AERODIGESTIVE_TRACT	MAP2K7 →	+1.271	+1.013	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	MAU2 →	+1.441	+0.985	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	RFX1 →	+0.974	+1.083	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,278 associations by consensus.

DNM2 vs SIN3B — BONE

Explore this scatter interactively →