DNM1P49

Across TCGA pan-cancer cohorts, DNM1P49 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DNM1P49 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DNM1P49 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DNM1P49 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

ACC, BLCA, and UCS are the cancer types where DNM1P49 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.285	0.809	.001	81	view →
BLCA	OS	Tertile	IV	0.120	0.599	<.001	72	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
LUAD	OS	Tertile	All	0.339	0.837	<.001	36	view →
UCEC	DFS	Tertile	All	0.736	0.899	.006	36	view →
PCPG	DFS	Tertile	All	0.079	0.774	<.001	36	view →
MESO	DFS	Tertile	All	0.099	0.392	.030	27	view →
ESCA	OS	Tertile	III,IV	1.000	0.377	.023	24	view →
GBM	OS	Tertile	All	0.152	0.424	<.001	18	view →
COAD	DFS	Tertile	All	0.445	0.796	.021	18	view →
PRAD	DFS	Tertile	All	0.737	0.935	.034	18	view →
LGG	DFS	Tertile	All	0.430	0.760	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DNM1P49–ACC (OS)

Open the ACC breakdown →