DNM1P47

Across TCGA pan-cancer cohorts, DNM1P47 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DNM1P47 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DNM1P47 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNM1P47 expression acts as an unfavorable survival marker.

LUAD, HNSC, and UCEC are the cancer types where DNM1P47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.296	0.793	<.001	18	view →
HNSC	OS	Median	All	0.476	0.769	.008	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
THYM	DFS	Median	III,IV	0.205	0.772	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DNM1P47–LUAD (DFS)

Open the LUAD breakdown →