DNM1P35

Across TCGA pan-cancer cohorts, DNM1P35 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DNM1P35 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher DNM1P35 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DNM1P35 expression acts as an unfavorable survival marker, although some lineages such as SARC show a favorable association.

ESCA, HNSC, and SARC are the cancer types where DNM1P35 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.325	0.711	.002	18	view →
HNSC	DFS	Median	All	0.098	0.710	<.001	12	view →
SARC	DFS	Median	All	1.000	0.357	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DNM1P35–ESCA (OS)

Open the ESCA breakdown →