DNM1P35

Across TCGA patient cohorts, DNM1P35 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. SARC shows the largest number of these associations.

The most reproducible DNM1P35-associated genes across cancer lineages are RN7SL134P, MIR6071, and RNA5SP198. Each is linked with DNM1P35 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNM1P35-to-partner and partner-to-DNM1P35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by DNM1P35-low versus DNM1P35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1P35→partner) and Y-score (partner→DNM1P35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.148	+3.599	.007	.001	3	2
CESC	MIR6071 →	+0.552	+4.320	.001	.007	3	2
CESC	RNA5SP198 →	+0.277	+5.144	<.001	.003	3	2
UCEC	MIR4470 →	+0.614	+3.450	<.001	.005	3	1
UCEC	LINC01050 →	+0.325	+3.064	<.001	.005	3	1
UCEC	BNIP3P4 →	+0.139	+3.747	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

RN7SL134P by DNM1P35 expression — UCEC

Explore this box plot interactively →