Across TCGA pan-cancer cohorts, DNM1P34 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DNM1P34’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DNM1P34 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DNM1P34 is over-expressed in tumor.
HNSC, UCEC, and BLCA are the cancer types where DNM1P34 tumor–normal differential expression is most reproducible.