DNM1P17

Across TCGA pan-cancer cohorts, DNM1P17 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of DNM1P17’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where DNM1P17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DNM1P17 is over-expressed in tumor, although a few such as READ and COAD show the opposite, repressed pattern.

STAD, LUAD, and HNSC are the cancer types where DNM1P17 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DNM1P17 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.120	<.001	5	view →
LUAD	All	All	+0.181	.004	4	view →
HNSC	All	All	+0.045	.010	4	view →
READ	All	All	−0.147	.033	2	view →
PRAD	All	All	+0.027	.039	2	view →
COAD	Female	All	−0.122	.042	1	view →
KIRC	All	II,III,IV	+0.035	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

DNM1P17–STAD

Open the STAD breakdown →