DNM1L

Across TCGA cell cohorts, DNM1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,894 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNM1L-associated GO terms across cancer lineages are Microtubule organizing center organization, Positive regulation of cell cycle, and Nucleocytoplasmic transport. Each is linked with DNM1L in more than 17 cancer types. Because this analysis shows association rather than direction, both DNM1L-to-partner and partner-to-DNM1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by DNM1L-low versus DNM1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1L→partner) and Y-score (partner→DNM1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule organizing center organization →	+0.088	+0.633	.004	.005	3	18
SOFT_TISSUE	Positive regulation of cell cycle →	+0.084	+0.626	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.091	+1.382	<.001	<.001	3	18
LUNG_SCLC	Centrosome cycle →	+0.081	+0.632	<.001	.001	3	18
LUNG_SCLC	Regulation of centrosome duplication →	+0.116	+0.827	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.082	+1.127	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,894 associations by consensus.

Microtubule organizing center organization by DNM1L expression — BONE

Explore this box plot interactively →