DNM1

Across TCGA patient cohorts, DNM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,451 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNM1-associated proteins across cancer lineages are TIMP2, PCOLCE, and COL3A1. Each is linked with DNM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNM1-to-partner and partner-to-DNM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNM1 versus TIMP2 in UCEC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1→partner) and Y-score (partner→DNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMP2 →	+0.558	+0.735	.002	.001	3	7
HNSC	PCOLCE →	+0.610	+0.766	<.001	<.001	3	7
BRCA	COL3A1 →	+0.905	+0.998	<.001	<.001	3	7
BRCA	COL5A1 →	+0.934	+0.717	.001	.003	3	7
OV	TUBB6 →	+0.457	+1.072	.002	.003	3	6
OV	VCAN →	+0.960	+1.250	.006	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,451 associations by consensus.

DNM1 vs TIMP2 — UCEC

Explore this scatter interactively →