DNM1

Across TCGA cell cohorts, DNM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,907 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DNM1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with DNM1 in more than 15 cancer types. Because this analysis shows association rather than direction, both DNM1-to-partner and partner-to-DNM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by DNM1-low versus DNM1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1→partner) and Y-score (partner→DNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of myoblast fusion →	+0.096	+2.576	<.001	<.001	3	16
STOMACH	Negative regulation of myoblast fusion →	+0.115	+2.846	.003	<.001	2	16
STOMACH	Cytoplasmic translation →	+0.077	+2.554	.005	.002	3	15
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+2.342	.004	.001	2	16
BREAST	Regulation of syncytium formation by plasma membrane fusion →	+0.097	+2.213	<.001	<.001	3	13
LUNG_SCLC	mRNA transport →	+0.076	+1.321	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,907 associations by consensus.

Regulation of myoblast fusion by DNM1 expression — BREAST

Explore this box plot interactively →