Across TCGA pan-cancer cohorts, DNLZ Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated DNLZ data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher DNLZ Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNLZ expression acts as an unfavorable survival marker.

UCS are the cancer types where DNLZ Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	All	0.126	0.523	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: DNLZ tumor-vs-normal RNA expression · all DNLZ data types