DND1

Across TCGA pan-cancer cohorts, DND1 Mutation is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated DND1 data layer compared with 1 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher DND1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DND1 expression acts as an unfavorable survival marker.

PAAD and UCEC are the cancer types where DND1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.131	0.613	.001	15	view →
UCEC	OS	Median	III,IV	0.061	0.588	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DND1–PAAD (OS)

Open the PAAD breakdown →