DNALI1

Across TCGA pan-cancer cohorts, DNALI1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated DNALI1 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DNALI1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DNALI1 expression acts as an unfavorable survival marker.

CCRCC, OV, and LUAD are the cancer types where DNALI1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.302	0.896	.015	12	view →
OV	DFS	Median	All	0.654	0.923	.035	8	view →
LUAD	DFS	Tertile	All	0.862	0.974	.006	8	view →
LSCC	DFS	Median	II,III,IV	0.824	1.000	.002	8	view →
UCEC	OS	Quartile	All	0.827	1.000	.017	4	view →
PDAC	DFS	Median	All	0.268	0.846	.038	3	view →
GBM	OS	Median	All	0.245	0.503	.017	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

DNALI1–CCRCC (OS)

Open the CCRCC breakdown →