DNALI1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNALI1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,780 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNALI1-associated genes across cancer lineages are SPEF1, SPATA17, and SAMD15. Each is linked with DNALI1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNALI1-to-partner and partner-to-DNALI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNALI1 versus SPEF1 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNALI1→partner) and Y-score (partner→DNALI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSPEF1 →+1.514+0.588<.001<.00137
GBMSPATA17 →+0.734+0.493<.001<.00136
UCECSAMD15 →+1.039+0.741<.001<.00136
OVOSCP1 →+0.878+0.719.001.00136
UCECCFAP94 →+1.152+0.837<.001<.00136
OVROPN1L →+2.078+0.860<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,780 associations by consensus.

DNALI1 vs SPEF1 — UCEC

Per-sample scatter of DNALI1 vs SPEF1 in UCEC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration