DNALI1

Across TCGA patient cohorts, DNALI1 mutation is significantly associated with the RNA expression of many other genes, with 385 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNALI1-associated genes across cancer lineages are RNA5SP422, RNA5SP414, and RNA5SP416. Each is linked with DNALI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DNALI1-to-partner and partner-to-DNALI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by DNALI1-low versus DNALI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNALI1→partner) and Y-score (partner→DNALI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+1.028	+2.408	<.001	.009	3	3
UCEC	RNA5SP414 →	+0.770	+2.992	<.001	.001	3	2
BRCA	RNA5SP416 →	+1.006	+8.471	<.001	.005	3	2
UCEC	RNA5SP423 →	+0.935	+2.454	<.001	.008	3	2
BRCA	MIR4307 →	+0.325	+7.731	<.001	.009	3	2
UCEC	RNA5SP412 →	+0.773	+2.704	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 385 associations by consensus.

RNA5SP422 by DNALI1 expression — UCEC

Explore this box plot interactively →