DNALI1

Across TCGA cell cohorts, DNALI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,070 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DNALI1-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Proton motive force-driven mitochondrial ATP synthesis, and ATP biosynthetic process. Each is linked with DNALI1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNALI1-to-partner and partner-to-DNALI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven ATP synthesis grouped by DNALI1-low versus DNALI1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNALI1→partner) and Y-score (partner→DNALI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Proton motive force-driven ATP synthesis →	+0.083	+1.878	<.001	<.001	3	7
CNS	Proton motive force-driven mitochondrial ATP synthesis →	+0.087	+1.974	<.001	<.001	3	7
CNS	ATP biosynthetic process →	+0.085	+1.748	<.001	<.001	3	7
LUNG_SCLC	Regulation of DNA-templated transcription initiation →	+0.081	+3.433	<.001	<.001	3	7
LUNG_SCLC	Positive regulation of DNA-templated transcription initiation →	+0.084	+3.454	<.001	<.001	3	7
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+4.126	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,070 associations by consensus.

Proton motive force-driven ATP synthesis by DNALI1 expression — CNS

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