DNAJC8

Across TCGA patient cohorts, DNAJC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,352 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNAJC8-associated proteins across cancer lineages are PPP1R8, NUDC, and LUZP1. Each is linked with DNAJC8 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAJC8-to-partner and partner-to-DNAJC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC8 versus PPP1R8 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC8→partner) and Y-score (partner→DNAJC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R8 →	+0.218	+0.217	<.001	.003	3	5
COAD	NUDC →	+0.552	+0.704	<.001	<.001	3	5
BRCA	LUZP1 →	+0.334	+0.401	.001	.001	2	6
GBM	YTHDF2 →	+0.316	+0.224	<.001	<.001	3	5
LSCC	ARID1A →	+0.341	+0.282	<.001	.006	3	4
GBM	STMN1 →	+0.608	+0.264	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,352 associations by consensus.

DNAJC8 vs PPP1R8 — GBM

Explore this scatter interactively →