DNAJC7

Across TCGA patient cohorts, DNAJC7 mutation is significantly associated with the RNA expression of many other genes, with 899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC7-associated genes across cancer lineages are RNA5SP412, FGF7P1, and ATF1P1. Each is linked with DNAJC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC7-to-partner and partner-to-DNAJC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by DNAJC7-low versus DNAJC7-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC7→partner) and Y-score (partner→DNAJC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP412 →	+0.168	+7.930	<.001	.008	3	2
BLCA	FGF7P1 →	+0.119	+7.640	<.001	.009	3	2
COAD	ATF1P1 →	+0.228	+6.392	.003	.001	3	1
COAD	NANOGP10 →	+0.169	+6.251	<.001	.001	3	1
COAD	SAR1AP4 →	+0.379	+5.212	<.001	.007	3	1
LUAD	TTTY6 →	+0.044	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 899 associations by consensus.

RNA5SP412 by DNAJC7 expression — LUAD

Explore this box plot interactively →