DNAJC7

Across TCGA cell cohorts, DNAJC7 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC7-associated genes across cancer lineages are PHOX2B, UCP1, and IL2. Each is linked with DNAJC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC7-to-partner and partner-to-DNAJC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHOX2B grouped by DNAJC7-low versus DNAJC7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC7→partner) and Y-score (partner→DNAJC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PHOX2B →	+0.024	+4.365	<.001	.002	3	1
BLOOD_Leukemia	UCP1 →	+0.181	+3.999	.004	.005	3	1
BLOOD_Leukemia	IL2 →	+0.794	+4.691	<.001	<.001	3	1
BLOOD_Leukemia	KIR2DL1 →	+0.056	+4.037	<.001	.004	3	1
BLOOD_Leukemia	DCLK3 →	+0.227	+3.769	<.001	.008	3	1
BLOOD_Leukemia	INSM2 →	+0.163	+3.769	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

PHOX2B by DNAJC7 expression — BLOOD_Leukemia

Explore this box plot interactively →