DNAJC7

Across TCGA cell cohorts, DNAJC7 mutation is significantly associated with the mutation status of many other genes, with 4,353 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC7-associated genes across cancer lineages are UBQLN4, PRMT1, and WDR81. Each is linked with DNAJC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAJC7-to-partner and partner-to-DNAJC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBQLN4 grouped by DNAJC7-low versus DNAJC7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC7→partner) and Y-score (partner→DNAJC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UBQLN4 →	+5.167	+4.787	<.001	<.001	1	4
LARGE_INTESTINE	PRMT1 →	+4.584	+3.350	.003	.003	1	4
UPPER_AERODIGESTIVE_TRACT	WDR81 →	+3.490	+3.490	.001	.001	1	4
UPPER_AERODIGESTIVE_TRACT	PRKCE →	+4.660	+3.539	.002	.002	1	3
BLOOD_Leukemia	PRR14L →	+3.845	+4.235	<.001	<.001	1	3
UPPER_AERODIGESTIVE_TRACT	TECPR2 →	+4.660	+3.539	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

UBQLN4 by DNAJC7 expression — BLOOD_Leukemia

Explore this box plot interactively →