DNAJC6

Across TCGA patient cohorts, DNAJC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,773 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNAJC6-associated proteins across cancer lineages are DNAJC6_S570, SEPTIN3, and TXNDC5. Each is linked with DNAJC6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAJC6-to-partner and partner-to-DNAJC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC6 versus DNAJC6_S570 in LSCC, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC6→partner) and Y-score (partner→DNAJC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNAJC6_S570 →	+1.030	+0.989	<.001	<.001	3	5
GBM	SEPTIN3 →	+0.838	+1.329	<.001	<.001	3	4
GBM	TXNDC5 →	-0.449	-0.691	<.001	<.001	3	4
LSCC	MAP2 →	+0.674	+0.559	.001	.003	3	4
COAD	PSMA3 →	-0.191	-0.574	.001	.003	3	3
COAD	PSMB1 →	-0.161	-0.501	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,773 associations by consensus.

DNAJC6 vs DNAJC6_S570 — LSCC

Explore this scatter interactively →