DNAJC6

Across TCGA cell cohorts, DNAJC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,784 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC6-associated GO terms across cancer lineages are Clathrin coat disassembly, Negative regulation of myoblast fusion, and Regulation of post-translational protein modification. Each is linked with DNAJC6 in more than 11 cancer types. Because this analysis shows association rather than direction, both DNAJC6-to-partner and partner-to-DNAJC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Clathrin coat disassembly grouped by DNAJC6-low versus DNAJC6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC6→partner) and Y-score (partner→DNAJC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Clathrin coat disassembly →	-0.193	-2.024	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.100	+1.008	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of post-translational protein modification →	+0.060	+1.214	<.001	<.001	3	9
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.085	+1.459	.005	.003	3	9
URINARY_TRACT	Viral translation →	+0.071	+1.543	.001	.001	2	9
LUNG_NSCLC_LUSC	Organelle membrane fusion →	+0.058	+1.115	.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Clathrin coat disassembly by DNAJC6 expression — URINARY_TRACT

Explore this box plot interactively →