DNAJC6

Across TCGA cell cohorts, DNAJC6 mutation is significantly associated with the mutation status of many other genes, with 3,615 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJC6-associated genes across cancer lineages are NDST4, AEBP1, and LAMC1. Each is linked with DNAJC6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAJC6-to-partner and partner-to-DNAJC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDST4 grouped by DNAJC6-low versus DNAJC6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC6→partner) and Y-score (partner→DNAJC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NDST4 →	+3.731	+3.554	.003	.003	1	5
BLOOD_Lymphoma	AEBP1 →	+3.316	+3.316	.006	.006	1	4
BLOOD_Lymphoma	LAMC1 →	+3.731	+3.554	.003	.003	1	4
BLOOD_Lymphoma	ADAMTS17 →	+3.146	+3.584	.001	.001	1	4
OVARY	NBEA →	+3.562	+4.684	.002	.002	1	4
BLOOD_Lymphoma	PPFIA3 →	+3.731	+3.554	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,615 associations by consensus.

NDST4 by DNAJC6 expression — BLOOD_Lymphoma

Explore this box plot interactively →