DNAJC5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNAJC5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,334 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNAJC5-associated genes across cancer lineages are PRKCA, GIT1, and TNXB. Each is linked with DNAJC5 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAJC5-to-partner and partner-to-DNAJC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC5 versus PRKCA in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC5→partner) and Y-score (partner→DNAJC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPRKCA →-0.685-0.466.001.00535
LSCCGIT1 →-0.629-0.235.002.00934
UCECTNXB →-1.203-0.372<.001<.00134
COADOSBPL2 →+0.440+0.196<.001.00134
UCECAKT3 →-0.942-0.408<.001<.00134
UCECSPARCL1 →-1.393-0.384<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,334 associations by consensus.

DNAJC5 vs PRKCA — BRCA

Per-sample scatter of DNAJC5 vs PRKCA in BRCA (Pearson r = -0.33).

Explore this scatter interactively →

Exploration