DNAJC30

Across TCGA pan-cancer cohorts, DNAJC30 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DNAJC30 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DNAJC30 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAJC30 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

UCEC, LUAD, and HNSC are the cancer types where DNAJC30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.775	0.974	.002	16	view →
LUAD	DFS	Quartile	II,III,IV	1.000	0.721	.003	10	view →
HNSC	OS	Median	All	0.344	1.000	.009	6	view →
LSCC	DFS	Median	All	0.862	0.694	.033	6	view →
CCRCC	DFS	Median	III,IV	0.399	0.932	.022	3	view →
PDAC	DFS	Tertile	All	0.629	0.818	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DNAJC30–UCEC (DFS)

Open the UCEC breakdown →