DNAJC30

Across TCGA cell cohorts, DNAJC30 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,840 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAJC30-associated GO terms across cancer lineages are Regulation of mitochondrial ATP synthesis coupled proton transport, Pre-mRNA catabolic process, and Protein-containing complex disassembly. Each is linked with DNAJC30 in more than 14 cancer types. Because this analysis shows association rather than direction, both DNAJC30-to-partner and partner-to-DNAJC30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial ATP synthesis coupled proton transport grouped by DNAJC30-low versus DNAJC30-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC30→partner) and Y-score (partner→DNAJC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of mitochondrial ATP synthesis coupled proton transport →	+0.131	+0.703	<.001	.001	3	15
SKIN	Pre-mRNA catabolic process →	+0.130	+0.591	<.001	.001	3	13
LUNG_NSCLC_LUSC	Protein-containing complex disassembly →	+0.083	+0.595	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Purine nucleoside triphosphate biosynthetic process →	+0.092	+0.808	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Purine ribonucleoside triphosphate biosynthetic process →	+0.092	+0.808	.001	<.001	3	10
SKIN	Vacuole organization →	+0.056	+0.840	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,840 associations by consensus.

Regulation of mitochondrial ATP synthesis coupled proton transport by DNAJC30 expression — LUNG_NSCLC_LUSC

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