DNAJC3

Across TCGA cell cohorts, DNAJC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,918 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DNAJC3-associated GO terms across cancer lineages are Positive regulation of translational initiation in response to stress, Positive regulation of translation in response to endoplasmic reticulum stress, and Cellular response to cold. Each is linked with DNAJC3 in more than 19 cancer types. Because this analysis shows association rather than direction, both DNAJC3-to-partner and partner-to-DNAJC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translational initiation in response to stress grouped by DNAJC3-low versus DNAJC3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC3→partner) and Y-score (partner→DNAJC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of translational initiation in response to stress →	+0.191	+1.199	<.001	<.001	3	20
URINARY_TRACT	Positive regulation of translation in response to endoplasmic reticulum stress →	+0.196	+1.243	<.001	<.001	3	20
URINARY_TRACT	Cellular response to cold →	+0.162	+1.007	<.001	<.001	3	20
LIVER	Regulation of translation initiation in response to endoplasmic reticulum stress →	+0.204	+1.162	<.001	.004	3	19
LUNG_SCLC	Regulation of translation in response to endoplasmic reticulum stress →	+0.150	+1.433	<.001	<.001	3	18
PANCREAS	Cellular response to topologically incorrect protein →	+0.076	+0.773	.008	.005	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,918 associations by consensus.

Positive regulation of translational initiation in response to stress by DNAJC3 expression — BONE

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