DNAJC3-DT

Across TCGA pan-cancer cohorts, DNAJC3-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated DNAJC3-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DNAJC3-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DNAJC3-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and MESO show a favorable association.

KIRC, MESO, and UCS are the cancer types where DNAJC3-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.859	0.638	<.001	63	view →
MESO	OS	Median	II,III,IV	0.664	0.458	.002	45	view →
UCS	DFS	Tertile	II,III,IV	0.560	0.137	.001	42	view →
LGG	DFS	Median	All	0.467	0.331	<.001	40	view →
KIRP	DFS	Median	All	0.977	0.796	.007	31	view →
COAD	DFS	Median	All	0.738	0.824	.005	20	view →
ESCA	DFS	Median	II,III,IV	0.280	0.408	.015	16	view →
HNSC	DFS	Median	IV	0.709	0.569	.009	15	view →
LIHC	DFS	Tertile	All	0.272	0.497	.019	14	view →
UVM	OS	Median	All	0.783	1.000	.014	13	view →
PAAD	DFS	Quartile	All	0.471	0.178	.005	12	view →
ACC	DFS	Tertile	IV	0.656	0.067	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

DNAJC3-DT–KIRC (DFS)

Open the KIRC breakdown →