DNAJC27-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DNAJC27-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated DNAJC27-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher DNAJC27-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DNAJC27-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and UCS show a favorable association.

LGG, UCS, and ACC are the cancer types where DNAJC27-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LGGOSMedianAll0.8690.748<.00143view →
UCSDFSMedianIII,IV0.5110.163.01538view →
ACCOSQuartileAll0.2521.000.00133view →
PAADOSMedianAll0.6840.345.00332view →
DLBCDFSMedianAll0.5841.000.00428view →
KIRCOSTertileAll0.8490.754.00324view →
MESOOSQuartileAll0.4740.251.01116view →
LUSCOSTertileAll0.8270.722.00912view →
LAMLDFSTertileAll0.4290.748.00612view →
BLCAOSTertileAll0.7040.527.00610view →
COADOSMedianIII,IV0.3630.747.0157view →
THYMDFSQuartileAll1.0000.720.0157view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration