DNAJC24

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DNAJC24 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DNAJC24 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DNAJC24 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DNAJC24 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and LSCC are the cancer types where DNAJC24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.7800.953<.0018view →
PDACOSTertileAll0.8141.000.0205view →
LSCCOSTertileAll0.6071.000.0274view →
LUADOSMedianII,III,IV0.3170.686.0364view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DNAJC24–CCRCC (OS)

Kaplan–Meier survival curve for DNAJC24 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration