DNAJC24

Across TCGA patient cohorts, DNAJC24 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC24-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, Ku80, and VHL. Each is linked with DNAJC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC24-to-partner and partner-to-DNAJC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by DNAJC24-low versus DNAJC24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC24→partner) and Y-score (partner→DNAJC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.555	+2.321	.029	.035	3	1
UCEC	Ku80 →	+0.289	+3.472	.015	.002	3	1
UCEC	VHL →	-1.140	-3.459	<.001	.005	3	1
UCEC	4E-BP1_pT37_T46 →	-0.420	-2.321	.026	.035	3	1
UCEC	Caspase-7-cleavedD198 →	+0.774	+3.189	.009	.010	3	1
UCEC	Cyclin-B1 →	+0.647	+2.321	.021	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Acetyl-a-Tubulin-Lys40 by DNAJC24 expression — UCEC

Explore this box plot interactively →