DNAJC24

Across TCGA cell cohorts, DNAJC24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,128 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC24-associated GO terms across cancer lineages are Protein histidyl modification to diphthamide, Peptidyl-histidine modification, and Regulation of protein K48-linked ubiquitination. Each is linked with DNAJC24 in more than 16 cancer types. Because this analysis shows association rather than direction, both DNAJC24-to-partner and partner-to-DNAJC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein histidyl modification to diphthamide grouped by DNAJC24-low versus DNAJC24-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC24→partner) and Y-score (partner→DNAJC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein histidyl modification to diphthamide →	+0.138	+1.020	<.001	.002	3	17
OESOPHAGUS	Peptidyl-histidine modification →	+0.138	+1.020	<.001	.002	3	17
BREAST	Regulation of protein K48-linked ubiquitination →	+0.118	+0.899	<.001	<.001	3	15
SOFT_TISSUE	Peptidyl-amino acid modification →	+0.028	+0.748	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.083	+0.974	<.001	<.001	3	14
SOFT_TISSUE	Microtubule organizing center organization →	+0.073	+0.675	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,128 associations by consensus.

Protein histidyl modification to diphthamide by DNAJC24 expression — OESOPHAGUS

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