DNAJC21

Across TCGA cell cohorts, DNAJC21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,279 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC21-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Cellular response to rapamycin, and Establishment of mitotic sister chromatid cohesion. Each is linked with DNAJC21 in more than 13 cancer types. Because this analysis shows association rather than direction, both DNAJC21-to-partner and partner-to-DNAJC21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by DNAJC21-low versus DNAJC21-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC21→partner) and Y-score (partner→DNAJC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Protein localization to nuclear inner membrane →	+0.153	+1.033	<.001	<.001	3	14
OVARY	Cellular response to rapamycin →	+0.154	+0.697	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.158	+0.937	<.001	.003	3	12
LIVER	Response to rapamycin →	+0.168	+0.796	.009	.005	2	13
LIVER	Protein localization to lipid droplet →	+0.234	+0.955	<.001	<.001	3	12
LIVER	Meiotic recombination checkpoint signaling →	+0.277	+0.747	.007	.004	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,279 associations by consensus.

Protein localization to nuclear inner membrane by DNAJC21 expression — LUNG_NSCLC_LUAD

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