DNAJC2

Across TCGA patient cohorts, DNAJC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,301 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAJC2-associated proteins across cancer lineages are HSPA14, DDX21, and DDX21_S89. Each is linked with DNAJC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DNAJC2-to-partner and partner-to-DNAJC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC2 versus HSPA14 in BRCA, with a Pearson correlation of 0.88.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC2→partner) and Y-score (partner→DNAJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSPA14 →	+0.547	+0.512	<.001	<.001	3	10
BRCA	DDX21 →	+0.604	+0.304	<.001	<.001	3	9
BRCA	DDX21_S89 →	+1.089	+0.314	<.001	<.001	3	9
LSCC	DDX56 →	+0.410	+0.365	<.001	<.001	3	9
LUAD	BZW2 →	+0.394	+0.268	<.001	<.001	3	9
BRCA	CDK1 →	+0.715	+0.308	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,301 associations by consensus.

DNAJC2 vs HSPA14 — BRCA

Explore this scatter interactively →