DNAJC2

Across TCGA cell cohorts, DNAJC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,388 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DNAJC2-associated GO terms across cancer lineages are DNA-templated transcription termination, tRNA processing, and Ribosome biogenesis. Each is linked with DNAJC2 in more than 16 cancer types. Because this analysis shows association rather than direction, both DNAJC2-to-partner and partner-to-DNAJC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by DNAJC2-low versus DNAJC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC2→partner) and Y-score (partner→DNAJC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription termination →	+0.116	+0.887	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	tRNA processing →	+0.075	+1.065	<.001	<.001	3	17
BONE	Ribosome biogenesis →	+0.121	+0.791	.004	.008	3	16
BONE	Replication fork processing →	+0.138	+1.075	.004	<.001	3	14
LIVER	Ribosome localization →	+0.129	+0.855	<.001	.006	3	14
UPPER_AERODIGESTIVE_TRACT	tRNA dihydrouridine synthesis →	+0.138	+0.813	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,388 associations by consensus.

DNA-templated transcription termination by DNAJC2 expression — BONE

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