DNAJC17

Across TCGA patient cohorts, DNAJC17 mutation is significantly associated with the RNA expression of many other genes, with 451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC17-associated genes across cancer lineages are RNU6-344P, SNX19P3, and LINC01650. Each is linked with DNAJC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC17-to-partner and partner-to-DNAJC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-344P grouped by DNAJC17-low versus DNAJC17-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC17→partner) and Y-score (partner→DNAJC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-344P →	+0.505	+5.279	.007	.006	3	2
SKCM	SNX19P3 →	+0.053	+3.428	.003	.009	3	2
BLCA	LINC01650 →	+0.119	+6.147	<.001	.002	3	2
SKCM	RPL36P19 →	+0.158	+3.240	<.001	.005	3	2
UCEC	ADM →	+1.277	+3.480	<.001	.002	3	1
UCEC	CAPN5 →	-0.718	-3.443	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

RNU6-344P by DNAJC17 expression — LUAD

Explore this box plot interactively →