DNAJC17

Across TCGA cell cohorts, DNAJC17 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,400 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DNAJC17-associated GO terms across cancer lineages are Cellular response to cisplatin, Regulation of translation at postsynapse, modulating synaptic transmission, and Protein-RNA complex disassembly. Each is linked with DNAJC17 in more than 10 cancer types. Because this analysis shows association rather than direction, both DNAJC17-to-partner and partner-to-DNAJC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to cisplatin grouped by DNAJC17-low versus DNAJC17-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC17→partner) and Y-score (partner→DNAJC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cellular response to cisplatin →	+0.132	+0.507	<.001	.007	3	11
LUNG_SCLC	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.099	+0.503	.002	.004	3	8
LUNG_SCLC	Protein-RNA complex disassembly →	+0.119	+0.766	.001	<.001	3	8
OVARY	Peptidyl-lysine hydroxylation →	+0.082	+0.735	.003	<.001	3	7
LUNG_NSCLC_LUAD	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.064	+0.720	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Regulation of protein ADP-ribosylation →	+0.154	+1.000	.004	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,400 associations by consensus.

Cellular response to cisplatin by DNAJC17 expression — STOMACH

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