DNAJC15

Across TCGA cell cohorts, DNAJC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,815 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DNAJC15-associated GO terms across cancer lineages are Regulation of cytoplasmic translation, Barbed-end actin filament capping, and Intrinsic apoptotic signaling pathway in response to oxidative stress. Each is linked with DNAJC15 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNAJC15-to-partner and partner-to-DNAJC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translation grouped by DNAJC15-low versus DNAJC15-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC15→partner) and Y-score (partner→DNAJC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of cytoplasmic translation →	-0.126	-2.151	.003	.001	3	8
BONE	Barbed-end actin filament capping →	+0.231	+2.287	<.001	<.001	3	6
BONE	Intrinsic apoptotic signaling pathway in response to oxidative stress →	+0.120	+2.448	<.001	<.001	3	6
STOMACH	Regulation of sodium ion export across plasma membrane →	+0.373	+1.718	<.001	<.001	3	6
STOMACH	Positive regulation of sodium ion export across plasma membrane →	+0.373	+1.718	<.001	<.001	3	6
BONE	Internal protein amino acid acetylation →	-0.152	-2.752	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,815 associations by consensus.

Regulation of cytoplasmic translation by DNAJC15 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →