DNAJC12

Across TCGA cell cohorts, DNAJC12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,637 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DNAJC12-associated GO terms across cancer lineages are Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator, Blood coagulation, intrinsic pathway, and Mitochondrial respiratory chain complex assembly. Each is linked with DNAJC12 in more than 9 cancer types. Because this analysis shows association rather than direction, both DNAJC12-to-partner and partner-to-DNAJC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator grouped by DNAJC12-low versus DNAJC12-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC12→partner) and Y-score (partner→DNAJC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator →	+0.116	+1.808	.001	.003	3	9
BONE	Blood coagulation, intrinsic pathway →	-0.188	-3.228	<.001	<.001	3	9
BONE	Mitochondrial respiratory chain complex assembly →	+0.073	+2.461	.008	.003	1	10
BONE	Intraciliary transport →	+0.066	+2.477	<.001	<.001	3	7
LUNG_SCLC	Membrane depolarization during SA node cell action potential →	+0.959	+2.385	<.001	<.001	3	7
BONE	Hexose transmembrane transport →	-0.094	-2.843	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,637 associations by consensus.

Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator by DNAJC12 expression — OESOPHAGUS

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