DNAJC10

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DNAJC10 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DNAJC10 data layer compared with 28 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DNAJC10 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAJC10 expression acts as an unfavorable survival marker.

COAD, LUAD, and UCEC are the cancer types where DNAJC10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll0.2130.699<.00134view →
LUADOSMedianII,III,IV0.0680.683<.00115view →
UCECOSMedianIV0.2310.592.0366view →
ACCDFSMedianAll0.1950.748.0033view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DNAJC10–COAD (DFS)

Kaplan–Meier survival curve for DNAJC10 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration