DNAJC10

Across TCGA cell cohorts, DNAJC10 mutation is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DNAJC10-associated genes across cancer lineages are PPP1R42, MGAT4D, and NEUROD4. Each is linked with DNAJC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC10-to-partner and partner-to-DNAJC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R42 grouped by DNAJC10-low versus DNAJC10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC10→partner) and Y-score (partner→DNAJC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PPP1R42 →	+0.123	+4.133	.002	.003	3	2
KIDNEY	MGAT4D →	+0.006	+5.000	<.001	.005	3	1
BLOOD_Lymphoma	NEUROD4 →	+0.156	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.127	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.046	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	DPPA2 →	+0.363	+4.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

PPP1R42 by DNAJC10 expression — BLOOD_Leukemia

Explore this box plot interactively →