DNAJC1

Across TCGA patient cohorts, DNAJC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,594 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DNAJC1-associated proteins across cancer lineages are TBC1D1, NIPSNAP2, and C8orf82. Each is linked with DNAJC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNAJC1-to-partner and partner-to-DNAJC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC1 versus TBC1D1 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC1→partner) and Y-score (partner→DNAJC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TBC1D1 →	+0.555	+0.607	<.001	.005	3	5
COAD	NIPSNAP2 →	-0.447	-0.522	<.001	<.001	3	4
GBM	C8orf82 →	-0.426	-0.354	<.001	.001	3	4
OV	PUS1 →	-0.396	-0.672	<.001	<.001	3	4
BRCA	DNAJC1_S430 →	+1.072	+1.341	<.001	<.001	3	4
BRCA	SIGIRR →	+0.596	+0.989	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,594 associations by consensus.

DNAJC1 vs TBC1D1 — OV

Explore this scatter interactively →