DNAJC1

Across TCGA patient cohorts, DNAJC1 protein abundance is significantly associated with the RNA expression of many other genes, with 21,640 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNAJC1-associated genes across cancer lineages are XBP1, NUFIP1, and ZNF783. Each is linked with DNAJC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNAJC1-to-partner and partner-to-DNAJC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAJC1 versus XBP1 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC1→partner) and Y-score (partner→DNAJC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XBP1 →	+1.587	+0.616	<.001	.001	3	8
COAD	NUFIP1 →	-0.595	-0.290	<.001	<.001	3	7
UCEC	ZNF783 →	-0.561	-0.331	.001	.003	3	7
LSCC	FARSB →	-0.553	-0.419	<.001	<.001	3	6
HNSC	CAMSAP2 →	-0.522	-0.507	<.001	<.001	3	6
LSCC	SYNCRIP →	-0.665	-0.472	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,640 associations by consensus.

DNAJC1 vs XBP1 — BRCA

Explore this scatter interactively →